Patients have ingested overdoses of up to 20g aciclovir on a single occasion, usually without toxic effects. Aciclovir 400 mg Tablets - Patient Information Leaflet (PIL) by Aurobindo Pharma - Milpharm Ltd. In a study of 20 male patients with normal sperm count, oral aciclovir administered at doses of up to 1g per day for up to six months has been shown to have no clinically significant effect on sperm count, motility or morphology.There have been no studies to investigate the effect of aciclovir on driving performance or the ability to operate machinery.

1 g Creme enthält 50 mg Aciclovir. 2 - 5 years: 400 mg Aciclovir four times daily. This belongs to a group of medicines called antivirals. Findings from reproduction toxicology studies are included in Section 5.3.Following oral administration of 200 mg Aciclovir five times a day, aciclovir has been detected in breast milk at concentrations ranging from 0.6 to 4.1 times the corresponding plasma levels. This site uses cookies. Many patients may be conveniently managed on a regimen of 400 mg Aciclovir twice daily at approximately twelve hourly intervals. When diluted in accordance with the recommended schedules, Aciclovir is known to be compatible with the following infusion fluids and stable for up to 12 hours at room temperature (15°C to 25°C): 1. Aciclovir triphosphate interferes with the viral DNA polymerase and inhibits viral DNA replication with resultant chain termination following its incorporation into the viral DNA.Prolonged or repeated courses of aciclovir in severely immuno-compromised individuals may result in the selection of virus strains with reduced sensitivity, which may not respond to continued aciclovir treatment. What Aciclovir 400 mg Tablets are and what they are used forAciclovir 400 mg Tablets contain a medicine called aciclovir. Accidental, repeated overdoses of oral aciclovir over several days have been associated with gastrointestinal effects (such as nausea and vomiting) and neurological effects (headache and confusion).Overdosage of intravenous aciclovir has resulted in elevations of serum creatinine, blood urea nitrogen and subsequent renal failure. Ingredient matches for Aciclovir 1A Pharma 400 mg Acyclovir. The mean aciclovir half-life during haemodialysis was 5.7 hours. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged.Odyssey Business Park, Ares Block, West End Road, South Ruislip, Middlesex, HA4 6QDTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. Continue typing to refine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged. What Aciclovir 400 mg Tablets are and what they are used for1. Ask your pharmacist how to throw away medicines you no longer use. By continuing to browse the site you are agreeing to our policy on the use of cookies. Continue typing to refine.

What you need to know before you take Aciclovir 400 mg Tablets 3. The clinical relevance of these findings is uncertain.Caution should however be exercised by balancing the potential benefits of treatment against any possible hazard. Not all pack sizes may be marketed. It treats infections caused by the herpes virus (herpes simplex), including: cold sores; genital herpes; Your doctor may prescribe aciclovir to prevent you getting these infections if you have had them before or you have a weak immune system. A detrimental effect on such activities cannot be predicted from the pharmacology of the active substance, but the adverse event profile should be borne in mind.The frequency categories associated with the adverse events below are estimates. The clinical relevance of these findings is uncertain.Largely reversible adverse effects on spermatogenesis in association with overall toxicity in rats and dogs have been reported only at doses of aciclovir greatly in excess of those employed therapeutically. Systemic administration of aciclovir in internationally accepted standard tests did not produce embryotoxic or teratogenic effects in rabbits, rats or mice.